Screening of solanum surrattense for antibacterial, antifungal, phytotoxic and haemagglutination.

ABSTRACT

OBJECTIVE: Plants produce a variety of useful bioactive materials that have been used to cure different ailments of human beings. With the same idea in mind, the crude methanolic extract and various fractions of Solanum surrattense were screened for antibacterial, antifungal, phytotoxic and heamagglutination activities. METHODS: Standardized assays were followed for the determination of antibacterial, antifungal phytotoxic and heamagglutination activity. RESULTS: The results of the antibacterial showed that crude methanolic extract was significantly active against Staphylococcus aureus (86%) The n-hexane fraction showed good activity against Pseudomonas aerogenosa (66.6%) and Bacillus subtilus (66.6%). The crude methanolic extract and various fractions were inactive against all test fungi. The crude methanolic extract, n-hexane, CHCl3 and aqueous fractions showed moderate phytotoxic activities of 46.67%, 40.00%, 33.34% and 33.34% respectively at 1000 microg/mL. The crude methanolic extract and various fractions S. surrattense were unable to agglutinate RBCs of the human blood indicating that this species lack phytolectins. CONCLUSION: The test sample showed significant antibacterial activity, no antifungal and heamagglutination activity while moderate phytotoxic was observed against Lemna minor L.