Entry to ß-alkoxyacrylates via gold-catalyzed intermolecular coupling of alkynoates and allylic ethers.
Org Lett
; 15(6): 1166-9, 2013 Mar 15.
Article
em En
| MEDLINE
| ID: mdl-23444917
ABSTRACT
The first gold-catalyzed intermolecular coupling of alkynoates and allylic ethers invoking alkoxy addition and [3,3]-sigmatropic rearrangement as the key mechanism has been developed. Remarkably, the reaction showed complete chemoselectivity toward the pathway initiated by the alkoxy addition to alkynes. This unprecedented reactivity led to a new access to diversely substituted ß-alkoxyacrylates in a highly efficient manner.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article