[A case of locally advanced sigmoid colon cancer curatively resected after neoadjuvant chemotherapy with FOLFIRI plus panitumumab].
Gan To Kagaku Ryoho
; 40(3): 397-9, 2013 Mar.
Article
em Ja
| MEDLINE
| ID: mdl-23507607
ABSTRACT
A 72-year-old woman having abdominal pain and high fever was diagnosed with KRAS wild-type sigmoid colon cancer, invading the urinary bladder and uterus with a pelvic abscess. Considering the difficulty of curative resection, we first performed sigmoid colostomy and abscess drainage. Remarkable tumor regression was indicated by CT and colonoscopy after 1 course of FOLFIRI and 5 courses of FOLFIRI+panitumumab. Following an additional 2 courses of panitumumab, sigmoidectomy and partialcystectomy were performed. Six courses of FOLFIRI+panitumumab were administered postoperatively and no recurrence has been observed for 7 months. FOLFIRI+panitumumab may be an effective preoperative chemotherapy for patients with KRAS wild-type locally advanced colon cancer.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias do Colo Sigmoide
/
Protocolos de Quimioterapia Combinada Antineoplásica
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Terapia Neoadjuvante
Limite:
Female
/
Humans
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Middle aged
Idioma:
Ja
Ano de publicação:
2013
Tipo de documento:
Article