CCRL2, a fringe member of the atypical chemoattractant receptor family.
Eur J Immunol
; 43(6): 1418-22, 2013 Jun.
Article
em En
| MEDLINE
| ID: mdl-23580473
ABSTRACT
The term atypical chemoattractant receptors is generally used to refer to a subset of G-protein-coupled receptors devoid of chemotactic activity and characterized by the ability to scavenge chemotactic factors from the inflammatory milieu. However, emerging evidence suggests that this class of receptors is heterogeneous in function. In this Viewpoint, we discuss the properties of CCRL2, a molecule devoid of ligand scavenging functions and suggested to regulate leukocyte recruitment by alternative mechanisms.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fatores Quimiotáticos
/
Receptores Acoplados a Proteínas G
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Receptores CCR
/
Leucócitos
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article