Diamond-lipid hybrids enhance chemotherapeutic tolerance and mediate tumor regression.
Adv Mater
; 25(26): 3532-41, 2013 Jul 12.
Article
em En
| MEDLINE
| ID: mdl-23584895
ABSTRACT
Self-assembled nanodiamond-lipid hybrid particles (NDLPs) harness the potent interaction between the nanodiamond (ND)-surface and small molecules, while providing a mechanism for cell-targeted imaging and therapy of triple negative breast cancers. Epidermal growth factor receptor-targeted NDLPs are highly biocompatible particles that provide cell-specific imaging, promote tumor retention of ND-complexes, prevent epirubicin toxicities and mediate regression of triple negative breast cancers.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias da Mama
/
Tolerância a Medicamentos
/
Nanodiamantes
/
Lipídeos
/
Antineoplásicos
Tipo de estudo:
Prognostic_studies
Limite:
Animals
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Female
/
Humans
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article