Association between variants of PRDM1 and NDP52 and Crohn's disease, based on exome sequencing and functional studies.
Gastroenterology
; 145(2): 339-47, 2013 Aug.
Article
em En
| MEDLINE
| ID: mdl-23624108
Palavras-chave
CD; Complex Disease; Crohn's disease; GWAS; IBD; IFN; Inflammatory Bowel Disease; NF-κB; PBL; PBMC; SNP; SNV; TLR; Toll-like receptor; UC; WT; Whole-Exome Sequencing; eQTL; expression quantitative trait locus; genome-wide association studies; inflammatory bowel disease; interferon; nuclear factor κB; peripheral blood lymphocyte; peripheral blood mononuclear cell; qRT-PCR; quantitative reverse-transcription polymerase chain reaction; single nucleotide polymorphism; single nucleotide variant; ulcerative colitis; wild-type
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Proteínas Repressoras
/
Proteínas Nucleares
/
Colite Ulcerativa
/
Doença de Crohn
Tipo de estudo:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article