Long noncoding RNAs in biology and hematopoiesis.
Blood
; 121(24): 4842-6, 2013 Jun 13.
Article
em En
| MEDLINE
| ID: mdl-23645840
ABSTRACT
Genome and transcriptome sequencing have revealed a rich assortment of noncoding RNAs in eukaryote cells, including long noncoding RNAs (lncRNAs), which regulate gene expression independent of protein coding potential. LncRNAs modulate protein coding gene expression in many cell types by regulating multiple processes, including epigenetic control of transcription, mRNA stability, and protein localization. Although little is known about lncRNAs in hematopoiesis, they are likely to exert widespread roles in this process.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transcrição Gênica
/
RNA Mensageiro
/
Estabilidade de RNA
/
Epigênese Genética
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RNA Longo não Codificante
/
Hematopoese
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article