[Improved methods for researching isolated carotid sinus baroreceptors automatically controlling for sinus pressure].
Zhongguo Ying Yong Sheng Li Xue Za Zhi
; 29(1): 11-4, 2013 Jan.
Article
em Zh
| MEDLINE
| ID: mdl-23662396
ABSTRACT
OBJECTIVE:
To develop a system for automatically controlling carotid sinus pressure in the study on baroreceptors.METHODS:
The preparation containing carotid sinus with parts of the connected vessels and carotid sinus nerve (CS-CSN) were isolated and perfused. A critical pressure controlling component (PRE-U, Hoerbiger, Deutschland) dictated by a computer was integrated into the system to clamp the intrasinus pressure. The pressure command and the relevant intrasinus pressure were compared to evaluate the validity of the pressure controlling system.RESULTS:
A variety of sinus pressure-controlling patterns, including pulsation, ramp and step pressures, could be achieved accurately by using the system, and the pressure-dependent discharge activities of sinus nerve were confirmed.CONCLUSION:
This system for clamping carotid sinus pressure could realize multiple pressure-controlling patterns and is a useful and flexible pressure controlling method that could applied in the study on mechano-electric transduction of baroreceptors.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pressorreceptores
/
Seio Carotídeo
/
Fibras Nervosas
Limite:
Animals
Idioma:
Zh
Ano de publicação:
2013
Tipo de documento:
Article