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Knockout of mouse Cyp3a gene enhances synthesis of cholesterol and bile acid in the liver.
Hashimoto, Mari; Kobayashi, Kaoru; Watanabe, Mio; Kazuki, Yasuhiro; Takehara, Shoko; Inaba, Asumi; Nitta, Shin-Ichiro; Senda, Naoto; Oshimura, Mitsuo; Chiba, Kan.
Afiliação
  • Hashimoto M; Laboratory of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba 260-8675, Japan.
  • Kobayashi K; Laboratory of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba 260-8675, Japan.
  • Watanabe M; Laboratory of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba 260-8675, Japan.
  • Kazuki Y; Department of Biomedical Science, Institute of Regenerative Medicine and Biofunction, Graduate School of Medical Science, Tottori University, Tottori 683-8503, Japan; Chromosome Engineering Research Center (CERC), Tottori University, Tottori 683-8503, Japan.
  • Takehara S; Chromosome Engineering Research Center (CERC), Tottori University, Tottori 683-8503, Japan.
  • Inaba A; Laboratory of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba 260-8675, Japan.
  • Nitta SI; Laboratory of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba 260-8675, Japan; Mitsubishi Chemical Medience Corporation, Ibaraki 305-0047, Japan.
  • Senda N; Mitsubishi Chemical Medience Corporation, Ibaraki 305-0047, Japan.
  • Oshimura M; Department of Biomedical Science, Institute of Regenerative Medicine and Biofunction, Graduate School of Medical Science, Tottori University, Tottori 683-8503, Japan; Chromosome Engineering Research Center (CERC), Tottori University, Tottori 683-8503, Japan.
  • Chiba K; Laboratory of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba 260-8675, Japan.
J Lipid Res ; 54(8): 2060-2068, 2013 Aug.
Article em En | MEDLINE | ID: mdl-23709690
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ácidos e Sais Biliares / Colesterol / Sistema Enzimático do Citocromo P-450 / Fígado Limite: Animals Idioma: En Ano de publicação: 2013 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ácidos e Sais Biliares / Colesterol / Sistema Enzimático do Citocromo P-450 / Fígado Limite: Animals Idioma: En Ano de publicação: 2013 Tipo de documento: Article