Immune competence in insect eggs depends on the extraembryonic serosa.
Dev Comp Immunol
; 41(2): 263-9, 2013 Oct.
Article
em En
| MEDLINE
| ID: mdl-23732406
ABSTRACT
Innate immunity is common to all metazoans and serves as a first line of defense against pathogens. Although the immune response of adult and larval insects has been well characterized, it remains unknown whether the insect egg is able to mount an immune response. Contrary to Drosophila, Tribolium eggs develop an extraembryonic epithelium, the serosa. Epithelia are well known for their ability to fight infection, so the serosa has the potential to protect the embryo against pathogens. To test this hypothesis we created serosa-less eggs by Tc-zen1 parental RNAi. We found that the Tribolium egg upregulates several immune genes to comparable levels as adults in response to infection. Drosophila eggs and serosa-less Tribolium eggs, however, show little to no upregulation of any of the tested immune genes. We conclude that the extraembryonic serosa is crucial for the early immune competence of the Tribolium egg.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Óvulo
/
Membrana Serosa
/
Tribolium
/
Expressão Gênica
/
Genes de Insetos
Limite:
Animals
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article