CTX-M-123, a novel hybrid of the CTX-M-1 and CTX-M-9 Group ß-lactamases recovered from Escherichia coli isolates in China.
Antimicrob Agents Chemother
; 57(8): 4068-71, 2013 Aug.
Article
em En
| MEDLINE
| ID: mdl-23752509
ABSTRACT
The chimeric bla(CTX-M-123) gene was identified in two ceftazidime-resistant Escherichia coli isolates from animals in different Chinese provinces. Like other CTX-M-1/9 group hybrids (CTX-M-64 and CTX-M-132), the ends (amino acids 1 to 135 and 234 to 291) of CTX-M-123 match CTX-M-15 while the central part (122 to 241) matches CTX-M-14. bla(CTX-M-123) is carried on related, but not identical, ~90-kb IncI1 plasmids in the two isolates, and one isolate simultaneously carries the group 1 blaCTX-M-55 gene on an additional IncI2 plasmid.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Beta-Lactamases
/
Proteínas de Escherichia coli
/
Escherichia coli
/
Proteínas Mutantes Quiméricas
/
Genes Bacterianos
Limite:
Animals
País/Região como assunto:
Asia
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article