Putative genes involved in saikosaponin biosynthesis in Bupleurum species.
Int J Mol Sci
; 14(6): 12806-26, 2013 Jun 19.
Article
em En
| MEDLINE
| ID: mdl-23783277
ABSTRACT
Alternative medicinal agents, such as the herb Bupleurum, are increasingly used in modern medicine to supplement synthetic drugs. First, we present a review of the currently known effects of triterpene saponins-saikosaponins of Bupleurum species. The putative biosynthetic pathway of saikosaponins in Bupleurum species is summarized, followed by discussions on identification and characterization of genes involved in the biosynthesis of saikosaponins. The purpose is to provide a brief review of gene extraction, functional characterization of isolated genes and assessment of expression patterns of genes encoding enzymes in the process of saikosaponin production in Bupleurum species, mainly B. kaoi. We focus on the effects of MeJA on saikosaponin production, transcription patterns of genes involved in biosynthesis and on functional depiction.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ácido Oleanólico
/
Saponinas
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Genes de Plantas
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Bupleurum
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Vias Biossintéticas
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article