Mitigate B1+ inhomogeneity using spatially selective radiofrequency excitation with generalized spatial encoding magnetic fields.
Magn Reson Med
; 71(4): 1458-69, 2014 Apr.
Article
em En
| MEDLINE
| ID: mdl-23794127
ABSTRACT
PURPOSE:
High-field magnetic resonance imaging (MRI) has the challenge of inhomogeneous B(1)(+), and consequently inhomogeneous flip angle distribution, which causes spatially dependent contrast and makes clinical diagnosis difficult.METHOD:
We propose a two-step pulse design procedure in which (1) a combination of linear and nonlinear spatial encoding magnetic fields (SEMs) is used to remap the B(1)(+) map in order to reduce the dimensionality of the problem, (2) the locations, amplitudes, and phases of spoke pulses are estimated in one dimension. The advantage of this B(1)(+) remapping is that when the isointensity contours of a linear combination of SEMs are similar to the isointensity contours of B(1)(+), a simple pulse sequence design using time-varying SEMs can achieve a homogenous flip-angle distribution efficiently.RESULTS:
We demonstrate that spatially selective radiofrequency (RF) excitation with generalized SEMs (SAGS) using both linear and quadratic SEMs in a multi-spoke k-space trajectory can mitigate the B(1)(+) inhomogeneity at 7T efficiently. Numerical simulations based on experimental data suggest that, compared with other methods, SAGS provide a formulation allowing multiple-pulse design, a similar average flip-angle distribution with less RF power, and/or a more homogeneous flip-angle distribution.CONCLUSION:
Without using multiple RF coils for parallel transmission, SAGS can be used to mitigate the B(1)(+) inhomogeneity in high-field MRI experiments.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Algoritmos
/
Encéfalo
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Imageamento por Ressonância Magnética
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Interpretação de Imagem Assistida por Computador
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Aumento da Imagem
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Armazenamento e Recuperação da Informação
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Artefatos
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article