Key molecular events during host cell invasion by Apicomplexan pathogens.
Curr Opin Microbiol
; 16(4): 432-7, 2013 Aug.
Article
em En
| MEDLINE
| ID: mdl-23895827
ABSTRACT
The ability of Apicomplexan parasites to invade host cells is key to their survival and pathogenesis. Plasmodium and Toxoplasma parasites share common mechanisms for invasion of host cells. Secretion of microneme and rhoptry proteins, tight junction formation and assembly of an acto-myosin motor are key steps for successful invasion by both parasites. Here, we review our understanding of the molecular basis for these steps.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Plasmodium
/
Toxoplasma
/
Endocitose
/
Interações Hospedeiro-Patógeno
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article