STAT3 expression, activity and functional consequences of STAT3 inhibition in esophageal squamous cell carcinomas and Barrett's adenocarcinomas.

Timme, S; Ihde, S; Fichter, C D; Waehle, V; Bogatyreva, L; Atanasov, K; Kohler, I; Schöpflin, A; Geddert, H; Faller, G; Klimstra, D; Tang, L; Reinheckel, T; Hauschke, D; Busch, H; Boerries, M; Werner, M; Lassmann, S

Timme, S; Ihde, S; Fichter, C D; Waehle, V; Bogatyreva, L; Atanasov, K; Kohler, I; Schöpflin, A; Geddert, H; Faller, G; Klimstra, D; Tang, L; Reinheckel, T; Hauschke, D; Busch, H; Boerries, M; Werner, M; Lassmann, S.

Afiliação

Timme S; Institute of Clinical Pathology, University Medical Center, Albert-Ludwigs-University, Freiburg, Germany.
Ihde S; Institute of Clinical Pathology, University Medical Center, Albert-Ludwigs-University, Freiburg, Germany.
Fichter CD; 1] Institute of Clinical Pathology, University Medical Center, Albert-Ludwigs-University, Freiburg, Germany [2] Faculty of Biology, Albert-Ludwigs-University, Freiburg, Germany.
Waehle V; Institute of Clinical Pathology, University Medical Center, Albert-Ludwigs-University, Freiburg, Germany.
Bogatyreva L; Institute of Medical Biometry and Medical Informatics, University Medical Center, Albert-Ludwigs-University, Freiburg, Germany.
Atanasov K; Institute of Clinical Pathology, University Medical Center, Albert-Ludwigs-University, Freiburg, Germany.
Kohler I; Institute of Clinical Pathology, University Medical Center, Albert-Ludwigs-University, Freiburg, Germany.
Schöpflin A; Institute of Clinical Pathology, University Medical Center, Albert-Ludwigs-University, Freiburg, Germany.
Geddert H; Department of Pathology, St Vincentius Kliniken, Karlsruhe, Germany.
Faller G; Department of Pathology, St Vincentius Kliniken, Karlsruhe, Germany.
Klimstra D; Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
Tang L; Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
Reinheckel T; 1] Institute of Molecular Medicine and Cell Research, University Medical Center, Albert-Ludwigs-University, Freiburg, Germany [2] BIOSS Centre for Biological Signalling Studies, Albert-Ludwigs-University, Freiburg, Germany [3] Comprehensive Cancer Center Freiburg, University Medical Center, Albert-L
Hauschke D; Institute of Medical Biometry and Medical Informatics, University Medical Center, Albert-Ludwigs-University, Freiburg, Germany.
Busch H; 1] Institute of Molecular Medicine and Cell Research, University Medical Center, Albert-Ludwigs-University, Freiburg, Germany [2] German Cancer Consortium (DKTK), Heidelberg, Germany [3] German Cancer Research Center (DKFZ), Heidelberg, Germany.
Boerries M; 1] Institute of Molecular Medicine and Cell Research, University Medical Center, Albert-Ludwigs-University, Freiburg, Germany [2] German Cancer Consortium (DKTK), Heidelberg, Germany [3] German Cancer Research Center (DKFZ), Heidelberg, Germany.
Werner M; 1] Institute of Clinical Pathology, University Medical Center, Albert-Ludwigs-University, Freiburg, Germany [2] Comprehensive Cancer Center Freiburg, University Medical Center, Albert-Ludwigs-University, Freiburg, Germany [3] German Cancer Consortium (DKTK), Heidelberg, Germany [4] German Cancer Res
Lassmann S; 1] Institute of Clinical Pathology, University Medical Center, Albert-Ludwigs-University, Freiburg, Germany [2] BIOSS Centre for Biological Signalling Studies, Albert-Ludwigs-University, Freiburg, Germany [3] Comprehensive Cancer Center Freiburg, University Medical Center, Albert-Ludwigs-University,

Oncogene ; 33(25): 3256-66, 2014 Jun 19.

Article em En | MEDLINE | ID: mdl-23912451

Assuntos

Adenocarcinoma/metabolismo; Esôfago de Barrett/metabolismo; Carcinoma de Células Escamosas/metabolismo; Neoplasias Esofágicas/metabolismo; Fator de Transcrição STAT3/antagonistas & inibidores; Fator de Transcrição STAT3/biossíntese; Adenocarcinoma/genética; Adenocarcinoma/patologia; Esôfago de Barrett/genética; Esôfago de Barrett/patologia; Carcinoma de Células Escamosas/genética; Carcinoma de Células Escamosas/patologia; Ciclo Celular/genética; Processos de Crescimento Celular/genética; Linhagem Celular Tumoral; Movimento Celular/genética; Regulação para Baixo; Neoplasias Esofágicas/genética; Neoplasias Esofágicas/patologia; Carcinoma de Células Escamosas do Esôfago; Técnicas de Silenciamento de Genes; Humanos; Fosforilação; Fator de Transcrição STAT3/genética; Fator de Transcrição STAT3/metabolismo; Transdução de Sinais; Regulação para Cima

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Esôfago de Barrett / Neoplasias Esofágicas / Carcinoma de Células Escamosas / Adenocarcinoma / Fator de Transcrição STAT3 Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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