Agonist-biased trafficking of somatostatin receptor 2A in enteric neurons.

Zhao, Peishen; Canals, Meritxell; Murphy, Jane E; Klingler, Diana; Eriksson, Emily M; Pelayo, Juan-Carlos; Hardt, Markus; Bunnett, Nigel W; Poole, Daniel P

Zhao, Peishen; Canals, Meritxell; Murphy, Jane E; Klingler, Diana; Eriksson, Emily M; Pelayo, Juan-Carlos; Hardt, Markus; Bunnett, Nigel W; Poole, Daniel P.

Afiliação

Zhao P; From the Monash Institute of Pharmaceutical Sciences, 381 Royal Parade, Parkville, Victoria 3052, Australia.
Canals M; From the Monash Institute of Pharmaceutical Sciences, 381 Royal Parade, Parkville, Victoria 3052, Australia.
Murphy JE; the Department of Surgery, University of California, San Francisco, San Francisco, California 94143.
Klingler D; the Department of Applied Oral Sciences, The Forsyth Institute, Cambridge, Massachusetts 02142, and.
Eriksson EM; the Division of Experimental Medicine, Department of Medicine, University of California, San Francisco, San Francisco, California 94110.
Pelayo JC; the Department of Surgery, University of California, San Francisco, San Francisco, California 94143.
Hardt M; the Department of Applied Oral Sciences, The Forsyth Institute, Cambridge, Massachusetts 02142, and.
Bunnett NW; From the Monash Institute of Pharmaceutical Sciences, 381 Royal Parade, Parkville, Victoria 3052, Australia,. Electronic address: Nigel.Bunnett@Monash.edu.
Poole DP; From the Monash Institute of Pharmaceutical Sciences, 381 Royal Parade, Parkville, Victoria 3052, Australia,. Electronic address: Daniel.Poole@Monash.edu.

J Biol Chem ; 288(36): 25689-25700, 2013 Sep 06.

Article em En | MEDLINE | ID: mdl-23913690

Assuntos

Sistema Nervoso Entérico/metabolismo; Neurônios/metabolismo; Proteólise; Receptores de Somatostatina/agonistas; Receptores de Somatostatina/metabolismo; Somatostatina-28/metabolismo; Somatostatina/metabolismo; Animais; Arrestinas/genética; Arrestinas/metabolismo; Ácido Aspártico Endopeptidases/genética; Ácido Aspártico Endopeptidases/metabolismo; Linhagem Celular Tumoral; Endossomos/genética; Endossomos/metabolismo; Enzimas Conversoras de Endotelina; Feminino; Fármacos Gastrointestinais/farmacologia; Complexo de Golgi/genética; Complexo de Golgi/metabolismo; Masculino; Metaloendopeptidases/genética; Metaloendopeptidases/metabolismo; Camundongos; Octreotida/farmacocinética; Transporte Proteico; Ratos; Ratos Sprague-Dawley; Receptores de Somatostatina/genética; Somatostatina/genética; Somatostatina-28/genética; beta-Arrestinas

Palavras-chave

Arrestin; Endocytosis; Endothelin-converting Enzyme; Neurons; Neuropeptide; Receptor Recycling; Somatostatin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Somatostatina / Receptores de Somatostatina / Sistema Nervoso Entérico / Somatostatina-28 / Proteólise / Neurônios Limite: Animals Idioma: En Ano de publicação: 2013 Tipo de documento: Article

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