Analyzing SNOMED CT and HL7 terminology binding for semantic interoperability on post-genomic clinical trials.
Stud Health Technol Inform
; 192: 980, 2013.
Article
em En
| MEDLINE
| ID: mdl-23920754
ABSTRACT
Current post-genomic clinical trials in cancer involve the collaboration of several institutions. Multi-centric retrospective analysis requires advanced methods to ensure semantic interoperability. In this scenario, the objective of the EU funded INTEGRATE project, is to provide an infrastructure to share knowledge and data in post-genomic breast cancer clinical trials. This paper presents the process carried out in this project, to bind domain terminologies in the area, such as SNOMED CT, with the HL7 v3 Reference Information Model (RIM). The proposed terminology binding follow the HL7 recommendations, but should also consider important issues such as overlapping concepts and domain terminology coverage. Although there are limitations due to the large heterogeneity of the data in the area, the proposed process has been successfully applied within the context of the INTEGRATE project. An improvement in semantic interoperability of patient data from modern breast cancer clinical trials, aims to enhance the clinical practice in oncology.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Processamento de Linguagem Natural
/
Neoplasias da Mama
/
Ensaios Clínicos como Assunto
/
Systematized Nomenclature of Medicine
/
Registros Eletrônicos de Saúde
/
Nível Sete de Saúde
/
Terminologia como Assunto
Tipo de estudo:
Guideline
/
Prognostic_studies
Limite:
Female
/
Humans
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article