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MRI compatible small animal monitoring and trigger system for whole body scanners.
Herrmann, Karl-Heinz; Pfeiffer, Norman; Krumbein, Ines; Herrmann, Lutz; Reichenbach, Jürgen R.
Afiliação
  • Herrmann KH; Medical Physics Group, Institute for Diagnostic and Interventional Radiology I, Jena University Hospital, Philosophenweg 3, Gebäude 5, 07743 Jena, Germany. Electronic address: karl-heinz.herrmann@med.uni-jena.de.
  • Pfeiffer N; Medical Physics Group, Institute for Diagnostic and Interventional Radiology I, Jena University Hospital, Philosophenweg 3, Gebäude 5, 07743 Jena, Germany; Ernst-Abbe-Fachhochschule Jena, Carl-Zeiss-Promenade 2, 07745 Jena, Germany.
  • Krumbein I; Medical Physics Group, Institute for Diagnostic and Interventional Radiology I, Jena University Hospital, Philosophenweg 3, Gebäude 5, 07743 Jena, Germany.
  • Herrmann L; Ernst-Abbe-Fachhochschule Jena, Carl-Zeiss-Promenade 2, 07745 Jena, Germany.
  • Reichenbach JR; Medical Physics Group, Institute for Diagnostic and Interventional Radiology I, Jena University Hospital, Philosophenweg 3, Gebäude 5, 07743 Jena, Germany.
Z Med Phys ; 24(1): 55-64, 2014 Mar.
Article em En | MEDLINE | ID: mdl-23962379
Performing magnetic resonance imaging (MRI) experiments with small animals requires continuous monitoring of vital parameters, especially the respiration rate. Clinical whole-body MR scanners represent an attractive option for preclinical imaging as dedicated animal scanners are cost-intensive in both investment and maintenance, thus limiting their availability. Even though impressive image quality is achievable with clinical MR systems in combination with special coils, their built-in physiologic monitoring and triggering units are often not suited for small animal imaging. In this work, we present a simple, MRI compatible low cost solution to monitor the respiration and heart rate of small animals in a clinical whole-body MR scanner. The recording and processing of the biosignals as well as the optimisation of the respiratory trigger generation is decribed. Additionally rat and mouse in-vivo MRI experiments are presented to illustrate the effectiveness of the monitoring and respiratory trigger system in suppressing motion artifacts.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Imageamento por Ressonância Magnética / Imagem Corporal Total / Técnicas de Imagem de Sincronização Cardíaca / Técnicas de Imagem de Sincronização Respiratória Tipo de estudo: Diagnostic_studies Limite: Animals Idioma: En Ano de publicação: 2014 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Imageamento por Ressonância Magnética / Imagem Corporal Total / Técnicas de Imagem de Sincronização Cardíaca / Técnicas de Imagem de Sincronização Respiratória Tipo de estudo: Diagnostic_studies Limite: Animals Idioma: En Ano de publicação: 2014 Tipo de documento: Article