[Pneumorenal syndrome induced by d-penicillamine: Goodpasture's syndrome or microscopic polyarteritis?]. / Syndrome pneumo-rénal induit par la d-pénicillamine: syndrome de Goodpasture ou polyartérite microscopique?
Rev Med Interne
; 11(2): 168-71, 1990.
Article
em Fr
| MEDLINE
| ID: mdl-2399379
ABSTRACT
Diffuse alveolar haemorrhage associated with glomerulonephritis is a rare but serious complication of d-penicillamine therapy. A case is reported which illustrates the usefulness of bronchoalveolar lavage and kidney needle biopsy for the early diagnosis of this condition. A search for antiglomerular basement membrane antibodies in serum was negative, whereas antigranulocyte cytoplasmic antibodies were present. These immunological results differentiated the disease from Goodpasture's syndrome to which it is clinically related and placed it in the same category as microscopic polyarteritis. After treatment with corticosteroids, cytostatic drugs and plasmapheresis, the outcome was favourable in contrast with the usually poor prognosis.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Penicilamina
/
Arterite
/
Glomerulonefrite
/
Hemorragia
/
Pneumopatias
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
/
Screening_studies
Limite:
Aged
/
Female
/
Humans
Idioma:
Fr
Ano de publicação:
1990
Tipo de documento:
Article