Combined inhibition of PI3K and activation of MAPK p38 signaling pathways trigger erythroid alternative splicing switch of 4.1R pre-mRNA in DMSO-induced erythroleukemia cells.
Cell Signal
; 25(12): 2453-61, 2013 Dec.
Article
em En
| MEDLINE
| ID: mdl-23993958
Palavras-chave
BFU-E; DMSO; EPO; EPO-R; ERK; Erythroid differentiation; Erythroleukemia; JAK2; Janus kinase-2; MAPK; MAPK p38; MEK; MEL; MTT; PI3K; SFFV; SR protein; STAT5; Signaling; burst forming unit-erythroid; dimethylsulfoxide; erythropoietin; erythropoietin receptor; extracellular signal-regulated kinase; mRNA splicing; methotrexate; mitogen-activated protein kinase; mitogen-activated protein kinase/extracellular signal-regulated kinase kinase; mouse erythroleukemia; phosphatidylinositol 3-kinase; serine-arginine-rich protein; signal transducers and activators of transcription factor-5; spleen focus forming virus
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Precursores de RNA
/
Leucemia Eritroblástica Aguda
/
Processamento Alternativo
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Fosfatidilinositol 3-Quinases
/
Proteínas Quinases p38 Ativadas por Mitógeno
Limite:
Animals
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article