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In-depth qualitative and quantitative analysis of composite glycosylation profiles and other micro-heterogeneity on intact monoclonal antibodies by high-resolution native mass spectrometry using a modified Orbitrap.
Rosati, Sara; van den Bremer, Ewald T J; Schuurman, Janine; Parren, Paul W H I; Kamerling, Johannis P; Heck, Albert J R.
Afiliação
  • Rosati S; Biomolecular Mass Spectrometry and Proteomics; Bijvoet Center for Biomolecular Research and Utrecht Institute of Pharmaceutical Sciences; Utrecht University; Utrecht, the Netherlands; Netherlands Proteomics Center; Utrecht, the Netherlands.
  • van den Bremer ET; Genmab; Utrecht, the Netherlands.
  • Schuurman J; Genmab; Utrecht, the Netherlands.
  • Parren PW; Genmab; Utrecht, the Netherlands.
  • Kamerling JP; Biomolecular Mass Spectrometry and Proteomics; Bijvoet Center for Biomolecular Research and Utrecht Institute of Pharmaceutical Sciences; Utrecht University; Utrecht, the Netherlands.
  • Heck AJ; Biomolecular Mass Spectrometry and Proteomics; Bijvoet Center for Biomolecular Research and Utrecht Institute of Pharmaceutical Sciences; Utrecht University; Utrecht, the Netherlands; Netherlands Proteomics Center; Utrecht, the Netherlands.
MAbs ; 5(6): 917-24, 2013.
Article em En | MEDLINE | ID: mdl-23995615
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Espectrometria de Massas / Imunoglobulina G / Anticorpos Monoclonais Tipo de estudo: Diagnostic_studies / Qualitative_research Idioma: En Ano de publicação: 2013 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Espectrometria de Massas / Imunoglobulina G / Anticorpos Monoclonais Tipo de estudo: Diagnostic_studies / Qualitative_research Idioma: En Ano de publicação: 2013 Tipo de documento: Article