Arginine residues on the opposite side of the active site stimulate the catalysis of ribosome depurination by ricin A chain by interacting with the P-protein stalk.

Li, Xiao-Ping; Kahn, Peter C; Kahn, Jennifer Nielsen; Grela, Przemyslaw; Tumer, Nilgun E

Li, Xiao-Ping; Kahn, Peter C; Kahn, Jennifer Nielsen; Grela, Przemyslaw; Tumer, Nilgun E.

Afiliação

Li XP; From the Departments of Plant Biology and Pathology and.
Kahn PC; Biochemistry and Microbiology, School of Environmental and Biological Sciences, Rutgers University, New Brunswick, New Jersey 08901-8520.
Kahn JN; From the Departments of Plant Biology and Pathology and.
Grela P; From the Departments of Plant Biology and Pathology and.
Tumer NE; From the Departments of Plant Biology and Pathology and. Electronic address: tumer@aesop.rutgers.edu.

J Biol Chem ; 288(42): 30270-30284, 2013 Oct 18.

Article em En | MEDLINE | ID: mdl-24003229

Assuntos

Adenina/química; Arginina/química; Ribossomos/química; Ricina/química; Saccharomyces cerevisiae/química; Arginina/genética; Catálise; Domínio Catalítico; Ligação Proteica; Ribossomos/genética; Ricina/genética

Palavras-chave

Protein Synthesis; RIP; Ribosomal RNA (rRNA); Ribosome-inactivating Protein; Ribosomes; Ricin; Toxins

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Arginina / Ribossomos / Ricina / Saccharomyces cerevisiae / Adenina Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2013 Tipo de documento: Article

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