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IntOGen-mutations identifies cancer drivers across tumor types.
Gonzalez-Perez, Abel; Perez-Llamas, Christian; Deu-Pons, Jordi; Tamborero, David; Schroeder, Michael P; Jene-Sanz, Alba; Santos, Alberto; Lopez-Bigas, Nuria.
Afiliação
  • Gonzalez-Perez A; Research Unit on Biomedical Informatics, Department of Experimental and Health Sciences, Pompeu Fabra University, Barcelona, Spain.
Nat Methods ; 10(11): 1081-2, 2013 Nov.
Article em En | MEDLINE | ID: mdl-24037244
The IntOGen-mutations platform (http://www.intogen.org/mutations/) summarizes somatic mutations, genes and pathways involved in tumorigenesis. It identifies and visualizes cancer drivers, analyzing 4,623 exomes from 13 cancer sites. It provides support to cancer researchers, aids the identification of drivers across tumor cohorts and helps rank mutations for better clinical decision-making.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Mutação / Neoplasias Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2013 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Mutação / Neoplasias Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2013 Tipo de documento: Article