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Balancing cationic and hydrophobic content of PEGylated siRNA polyplexes enhances endosome escape, stability, blood circulation time, and bioactivity in vivo.
Nelson, Christopher E; Kintzing, James R; Hanna, Ann; Shannon, Joshua M; Gupta, Mukesh K; Duvall, Craig L.
Afiliação
  • Nelson CE; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA.
  • Kintzing JR; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA.
  • Hanna A; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA.
  • Shannon JM; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA.
  • Gupta MK; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA.
  • Duvall CL; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA.
ACS Nano ; 7(10): 8870-80, 2013 Oct 22.
Article em En | MEDLINE | ID: mdl-24041122
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polietilenoglicóis / Endossomos / Circulação Sanguínea / RNA Interferente Pequeno Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2013 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polietilenoglicóis / Endossomos / Circulação Sanguínea / RNA Interferente Pequeno Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2013 Tipo de documento: Article