Prognostic implications of changes in cardiac troponin I levels in patients with non-ST elevation acute coronary syndrome.
Biomarkers
; 18(8): 668-72, 2013 Dec.
Article
em En
| MEDLINE
| ID: mdl-24083422
ABSTRACT
OBJECTIVE:
Information is limited on the prognostic implications of cardiac troponin I (cTnI) changes during the first days of non-ST elevation acute coronary syndrome (NSTE-ACS).METHODS:
High-sensitivity cTnI levels were measured at study inclusion and after 48 h in 1615 conservatively managed NSTE-ACS patients from the Global Use of Strategies To Open Occluded Coronary Arteries (GUSTO) IV trial.RESULTS:
Patients with moderately increased cTnI levels and without a relevant decrease over time had a significantly raised mortality at 30 days and 1 year. No relevant associations between cTnI changes and recurrent myocardial infarction were seen.CONCLUSION:
The cTnI change is predictive for subsequent mortality in selected conservatively managed NSTE-ACS patients.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Troponina I
/
Síndrome Coronariana Aguda
/
Miocárdio
Tipo de estudo:
Clinical_trials
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article