D-psicose increases energy expenditure and decreases body fat accumulation in rats fed a high-sucrose diet.
Int J Food Sci Nutr
; 65(2): 245-50, 2014 Mar.
Article
em En
| MEDLINE
| ID: mdl-24144428
ABSTRACT
We investigated the anti-obesity effects of D-psicose by increasing energy expenditure in rats pair-fed the high-sucrose diet (HSD). Wistar rats were divided into two dietary groups HSD containing 5% cellulose (C) and 5% d-psicose (P). The C dietary group was further subdivided into two groups rats fed the C diet ad libitum (C-AD) and pair-fed the C diet along with those in the P group (C-PF). Resting energy expenditure during darkness and lipoprotein lipase activity in the soleus muscle were significantly higher in the P group than in the C-PF group. Serum levels of glucose, leptin and adiponectin; glucose-6-phosphate dehydrogenase activities in the liver and perirenal adipose tissue; and body fat accumulation were all significantly lower in the P group than in the C-PF group. The anti-obesity effects of D-psicose could be induced not only by suppressing lipogenic enzyme activity but also by increasing EE in rats.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Tecido Adiposo
/
Sacarose Alimentar
/
Fármacos Antiobesidade
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Dieta
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Metabolismo Energético
/
Frutose
/
Obesidade
Tipo de estudo:
Health_economic_evaluation
Limite:
Animals
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article