Atypical RNAs in the coelacanth transcriptome.
J Exp Zool B Mol Dev Evol
; 322(6): 342-51, 2014 Sep.
Article
em En
| MEDLINE
| ID: mdl-24174405
ABSTRACT
Circular and apparently trans-spliced RNAs have recently been reported as abundant types of transcripts in mammalian transcriptome data. Both types of non-colinear RNAs are also abundant in RNA-seq of different tissue from both the African and the Indonesian coelacanth. We observe more than 8,000 lincRNAs with normal gene structure and several thousands of circularized and trans-spliced products, showing that such atypical RNAs form a substantial contribution to the transcriptome. Surprisingly, the majority of the circularizing and trans-connecting splice junctions are unique to atypical forms, that is, are not used in normal isoforms.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
RNA
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Splicing de RNA
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Transcriptoma
/
Peixes
Limite:
Animals
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article