Assembly of pyrene-modified DNA/RNA duplexes incorporating a G-rich single strand region.
Bioorg Med Chem Lett
; 23(24): 6822-4, 2013 Dec 15.
Article
em En
| MEDLINE
| ID: mdl-24183539
ABSTRACT
The structural properties of a DNA/RNA duplex having a pyrene residue at the 5' end of DNA and a G-rich single strand region at the 3' end of RNA were studied in detail. Fluorescence and ultracentrifugation analyses indicated the formation of a complex containing four DNA/RNA duplexes, which required a pyrene residue, G-rich sequence, RNA-type backbone, and high salt concentration.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pirenos
/
DNA
/
RNA
/
Guanina
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article