[Sick sinus syndrome possibly due to lopinavir-ritonavir: report of two cases].
Kansenshogaku Zasshi
; 87(5): 613-7, 2013 Sep.
Article
em Ja
| MEDLINE
| ID: mdl-24195172
ABSTRACT
We describe herein two cases of sick sinus syndrome possibly due to lopinavir-ritonavir in HIV-infected individuals. The heart rate dropped to 30 to 40 beats per minute in both cases, but patients remained asymptomatic and recovered promptly after discontinuation of lopinavir-ritonavir. The time until onset varied; one patient developed bradyarrhythmia 9 days after the initial dose, and another 4 hours after. Since lopinavir-ritonavir is a frequently used antiretroviral agent, clinicians must be aware of this potentially lethal adverse effect.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Síndrome do Nó Sinusal
/
Ritonavir
/
Antirretrovirais
/
Lopinavir
Limite:
Aged
/
Humans
/
Male
/
Middle aged
Idioma:
Ja
Ano de publicação:
2013
Tipo de documento:
Article