Preparation of chiral bromomethylenecyclopropane and its use in Suzuki-Miyaura coupling: synthesis of the arylmethyl-(Z)-cyclopropane structure core.

Tanabe, Makoto; Watanabe, Mizuki; Hoshiya, Naoyuki; Mizuno, Akira; Fukuda, Hayato; Arisawa, Mitsuhiro; Shuto, Satoshi

Tanabe, Makoto; Watanabe, Mizuki; Hoshiya, Naoyuki; Mizuno, Akira; Fukuda, Hayato; Arisawa, Mitsuhiro; Shuto, Satoshi.

Afiliação

Tanabe M; Faculty of Pharmaceutical Sciences and Center for Research and Education on Drug Development, Hokkaido University , Kita-12, Nishi-6, Kita-ku, Sapporo 060-0812, Japan.

J Org Chem ; 78(23): 11714-20, 2013 Dec 06.

Article em En | MEDLINE | ID: mdl-24206361

ABSTRACT

ABSTRACT

A preparative method for an optically active bromomethylenecyclopropane unit and its practical conversion to (Z)-cyclopropane-containing chiral compounds via Suzuki-Miyaura coupling were established.

Assuntos

Ciclopropanos/síntese química; Hidrocarbonetos Bromados/síntese química; Ciclopropanos/química; Hidrocarbonetos Bromados/química; Estrutura Molecular; Estereoisomerismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ciclopropanos / Hidrocarbonetos Bromados Idioma: En Ano de publicação: 2013 Tipo de documento: Article

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