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Early pharmaceutical profiling to predict oral drug absorption: current status and unmet needs.
Bergström, Christel A S; Holm, René; Jørgensen, Søren Astrup; Andersson, Sara B E; Artursson, Per; Beato, Stefania; Borde, Anders; Box, Karl; Brewster, Marcus; Dressman, Jennifer; Feng, Kung-I; Halbert, Gavin; Kostewicz, Edmund; McAllister, Mark; Muenster, Uwe; Thinnes, Julian; Taylor, Robert; Mullertz, Anette.
Afiliação
  • Bergström CA; Department of Pharmacy, Uppsala University, Biomedical Centre P.O. Box 580, SE-751 23 Uppsala, Sweden. Electronic address: christel.bergstrom@farmaci.uu.se.
  • Holm R; Biologics and Pharmaceutical Science, H. Lundbeck A/S, Ottiliavej 9, DK-2500 Valby, Denmark.
  • Jørgensen SA; Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen, Denmark.
  • Andersson SB; Department of Pharmacy, Uppsala University, Biomedical Centre P.O. Box 580, SE-751 23 Uppsala, Sweden.
  • Artursson P; Department of Pharmacy, Uppsala University, Biomedical Centre P.O. Box 580, SE-751 23 Uppsala, Sweden.
  • Beato S; Novartis Pharma AG, Novartis Campus, CH-4056 Basel, Switzerland.
  • Borde A; Pharmaceutical Development, AstraZeneca R&D, Mölndal, Sweden.
  • Box K; Sirius Analytical Instruments Ltd., Riverside, Forest Row Business Park, Forest Row, East Sussex RH18 5DW, UK.
  • Brewster M; ChemPharm Development, Johnson & Johnson Pharmaceutical Research & Development, 2340 Beerse, Belgium.
  • Dressman J; Institute of Pharmaceutical Technology, Goethe Universität, 60438 Frankfurt/Main, Germany.
  • Feng KI; Basic Pharmaceutical Sciences, Merck Research Laboratories, Merck & Co., Inc., USA.
  • Halbert G; Strathclyde Institute for Pharmacy and Biomedical Sciences, Robertson Wing, University of Strathclyde, 161 Cathedral Street, Glasgow G4 0RE, Scotland, UK.
  • Kostewicz E; Institute of Pharmaceutical Technology, Goethe Universität, 60438 Frankfurt/Main, Germany.
  • McAllister M; Drug Product Design, Pfizer PGRD, Sandwich, Kent CT13 9NJ, UK.
  • Muenster U; Material Science and Early Characterization, Bayer Pharma AG, Research Site Wuppertal-Aprath, Germany.
  • Thinnes J; Institute of Pharmaceutical Technology, Goethe Universität, 60438 Frankfurt/Main, Germany.
  • Taylor R; Sirius Analytical Instruments Ltd., Riverside, Forest Row Business Park, Forest Row, East Sussex RH18 5DW, UK.
  • Mullertz A; Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen, Denmark.
Eur J Pharm Sci ; 57: 173-99, 2014 Jun 16.
Article em En | MEDLINE | ID: mdl-24215735
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Biofarmácia / Farmacocinética / Preparações Farmacêuticas / Tecnologia Farmacêutica / Trato Gastrointestinal / Absorção Intestinal Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Biofarmácia / Farmacocinética / Preparações Farmacêuticas / Tecnologia Farmacêutica / Trato Gastrointestinal / Absorção Intestinal Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article