Extracellular generation of adenosine by the ectonucleotidases CD39 and CD73 promotes dermal fibrosis.

Fernández, Patricia; Perez-Aso, Miguel; Smith, Gideon; Wilder, Tuere; Trzaska, Sean; Chiriboga, Luis; Franks, Andrew; Robson, Simon C; Cronstein, Bruce N; Chan, Edwin S L

Fernández, Patricia; Perez-Aso, Miguel; Smith, Gideon; Wilder, Tuere; Trzaska, Sean; Chiriboga, Luis; Franks, Andrew; Robson, Simon C; Cronstein, Bruce N; Chan, Edwin S L.

Afiliação

Fernández P; Departments of Medicine and Dermatology, New York University School of Medicine, New York, New York.
Perez-Aso M; Departments of Medicine and Dermatology, New York University School of Medicine, New York, New York.
Smith G; Division of Gastroenterology, Department of Medicine, Harvard Medical School, Boston, Massachusetts.
Wilder T; Departments of Medicine and Dermatology, New York University School of Medicine, New York, New York.
Trzaska S; Departments of Medicine and Dermatology, New York University School of Medicine, New York, New York.
Chiriboga L; Departments of Medicine and Dermatology, New York University School of Medicine, New York, New York.
Franks A; Departments of Medicine and Dermatology, New York University School of Medicine, New York, New York.
Robson SC; Division of Gastroenterology, Department of Medicine, Harvard Medical School, Boston, Massachusetts.
Cronstein BN; Departments of Medicine and Dermatology, New York University School of Medicine, New York, New York.
Chan ESL; Departments of Medicine and Dermatology, New York University School of Medicine, New York, New York. Electronic address: chane01@nyu.edu.

Am J Pathol ; 183(6): 1740-1746, 2013 Dec.

Article em En | MEDLINE | ID: mdl-24266925

Assuntos

5'-Nucleotidase; Adenosina; Antígenos CD; Apirase; Derme; Escleroderma Sistêmico; 5'-Nucleotidase/genética; 5'-Nucleotidase/metabolismo; Adenosina/genética; Adenosina/metabolismo; Animais; Antibióticos Antineoplásicos/efeitos adversos; Antibióticos Antineoplásicos/farmacologia; Antígenos CD/genética; Antígenos CD/metabolismo; Apirase/genética; Apirase/metabolismo; Bleomicina/efeitos adversos; Bleomicina/farmacologia; Derme/metabolismo; Derme/patologia; Fibrose/induzido quimicamente; Fibrose/genética; Fibrose/metabolismo; Fibrose/patologia; Camundongos; Camundongos Knockout; Escleroderma Sistêmico/induzido quimicamente; Escleroderma Sistêmico/genética; Escleroderma Sistêmico/metabolismo; Escleroderma Sistêmico/patologia; Fator de Crescimento Transformador beta1/genética; Fator de Crescimento Transformador beta1/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Apirase / Escleroderma Sistêmico / Antígenos CD / 5'-Nucleotidase / Adenosina / Derme Limite: Animals Idioma: En Ano de publicação: 2013 Tipo de documento: Article

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