Electrical impedance myography correlates with standard measures of ALS severity.
Muscle Nerve
; 49(3): 441-3, 2014 Mar.
Article
em En
| MEDLINE
| ID: mdl-24273034
ABSTRACT
INTRODUCTION:
Electrical impedance myography (EIM) can be used to assess amyotrophic lateral sclerosis (ALS) progression. The relationship between EIM values and standard assessment measures, however, is unknown.METHODS:
EIM 50 kHz phase data from 60 subjects who participated in a longitudinal natural history study of ALS were correlated with handheld dynamometry (HHD), the ALS Functional Rating Scale-Revised (ALSFRS-R) score, and motor unit number estimation (MUNE).RESULTS:
Moderate strength correlations between EIM parameters and HHD were observed for both whole-body and individual upper and lower extremity values. Similarly, moderate strength correlations were observed between EIM and ALSFRS-R upper and lower extremity subscores, but not total ALSFRS-R scores. MUNE correlated significantly with single muscle EIM data but not with whole body or upper or lower extremity values.CONCLUSIONS:
These results support the concept that EIM can serve as a meaningful measure of disease severity in ALS.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Impedância Elétrica
/
Músculo Esquelético
/
Esclerose Lateral Amiotrófica
/
Miografia
Limite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article