Self-assembled fluorescent organic nanoparticles for live-cell imaging.
Chemistry
; 19(49): 16646-50, 2013 Dec 02.
Article
em En
| MEDLINE
| ID: mdl-24281811
ABSTRACT
Fluorescent, cell-permeable, organic nanoparticles based on self-assembled π-conjugated oligomers with high absorption cross-sections and high quantum yields have been developed. The nanoparticles are generated with a tuneable density of amino groups for charge-mediated cellular uptake by a straightforward self-assembly protocol, which allows for control over size and toxicity. The results show that a single amino group per ten oligomers is sufficient to achieve cellular uptake. The non-toxic nanoparticles are suitable for both one- and two-photon cellular imaging and flow cytometry, and undergo very efficient cellular uptake.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Nanopartículas
/
Corantes Fluorescentes
Limite:
Humans
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article