Carbon-14 labeling of K777â¢HCl, a therapeutic agent for Chagas disease.
J Labelled Comp Radiopharm
; 56(9-10): 461-3, 2013.
Article
em En
| MEDLINE
| ID: mdl-24285521
ABSTRACT
The antitrypanosomal agent K777â¢HCl was labeled with carbon-14 to support absorption, distribution, metabolism, and excretion studies of this potential new drug for the treatment of Chagas disease. The radiolabeled compound was prepared in eight steps from [(14) C(U)]-(l)-phenylalanine with a specific activity of 54.4 mCi/mmol and an overall radiochemical yield of 4.1%.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Compostos de Vinila
/
Doença de Chagas
/
Dipeptídeos
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article