[Clinical efficacy and safety of megestrol acetate vaginal ring].
Zhonghua Yi Xue Za Zhi
; 93(31): 2490-2, 2013 Aug 20.
Article
em Zh
| MEDLINE
| ID: mdl-24300272
ABSTRACT
OBJECTIVE:
To explore the efficacy and safety of megestrol acetate silicone vaginal ring.METHODS:
A total of 165 healthy child-bearing age women were recruited to examine the efficacy, safety and satisfaction rate of megestrol acetate silicone vaginal ring.RESULTS:
The cumulative pregnancy rate of megestrol acetate silicone vaginal ring was 3.93%. And its discontinuation rate was 2.54%, the incidence of adverse events 11.52% and the incidence of adverse effects 1.81% while the symptoms were all slight. The bleeding pattern was similar to that of normal menstruation. Compared with baseline, the elevated level of triglycerides and the reduced level of low-density lipoprotein (LDL) were significantly different while no significant difference existed in high-density lipoprotein (HDL), cholesterol and hemoglobin, etc. The satisfaction rate of megestrol acetate silicone vaginal ring was 94.6% and increased with time.CONCLUSION:
Megestrol acetate silicone vaginal ring is an effective and safe option of contraceptives.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Dispositivos Anticoncepcionais Femininos
/
Acetato de Megestrol
Limite:
Adult
/
Female
/
Humans
/
Pregnancy
Idioma:
Zh
Ano de publicação:
2013
Tipo de documento:
Article