GSK3ß negatively regulates HIF1&#945; mRNA stability via nucleolin in the MG63 osteosarcoma cell line.

Cheng, Dong-dong; Zhao, Hai-guang; Yang, Yun-song; Hu, Tu; Yang, Qing-cheng

GSK3ß negatively regulates HIF1α mRNA stability via nucleolin in the MG63 osteosarcoma cell line.

Cheng, Dong-dong; Zhao, Hai-guang; Yang, Yun-song; Hu, Tu; Yang, Qing-cheng.

Afiliação

Cheng DD; Department of Orthopeadics, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233, China.
Zhao HG; Department of Vascular Surgery, Shanghai Jiao Tong University Affiliated Ninth People's Hospital, Shanghai 200011, China.
Yang YS; Huazhong University of Science and Technology, Wuhan 430074, China.
Hu T; Department of Orthopeadics, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233, China.
Yang QC; Department of Orthopeadics, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233, China. Electronic address: tjyqc@163.com.

Biochem Biophys Res Commun ; 443(2): 598-603, 2014 Jan 10.

Article em En | MEDLINE | ID: mdl-24333432

Assuntos

Subunidade alfa do Fator 1 Induzível por Hipóxia/metabolismo; Osteossarcoma/metabolismo; Fosfoproteínas/metabolismo; Estabilidade de RNA/fisiologia; RNA Mensageiro/metabolismo; Proteínas de Ligação a RNA/metabolismo; Linhagem Celular Tumoral; Regulação para Baixo; Humanos; RNA Mensageiro/genética; Nucleolina

Palavras-chave

ARNT; Chx; EPO; GLUT1; GSK3ß; HIF1α; Nucleolin; ODD; Osteosarcoma; SDSPAGE; VEGF; VHL; aryl hydrocarbon receptor nuclear translocator; cycloheximide; erythropoietin; glucose transporter 1; glycogen synthase kinase 3 beta; hypoxia-inducible factor 1α; mRNA; oxygen-dependent degradation; siRNA; small interfering RNA; sodium dodecyl sulfate polyacrylamide gel electrophoresis; vascular endothelial growth factor; von Hippel-Lindau

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfoproteínas / RNA Mensageiro / Osteossarcoma / Proteínas de Ligação a RNA / Estabilidade de RNA / Subunidade alfa do Fator 1 Induzível por Hipóxia Limite: Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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