Fish intake during pregnancy, fetal growth, and gestational length in 19 European birth cohort studies.
Am J Clin Nutr
; 99(3): 506-16, 2014 Mar.
Article
em En
| MEDLINE
| ID: mdl-24335057
ABSTRACT
BACKGROUND:
Fish is a rich source of essential nutrients for fetal development, but in contrast, it is also a well-known route of exposure to environmental pollutants.OBJECTIVE:
We assessed whether fish intake during pregnancy is associated with fetal growth and the length of gestation in a panel of European birth cohort studies.DESIGN:
The study sample of 151,880 mother-child pairs was derived from 19 population-based European birth cohort studies. Individual data from cohorts were pooled and harmonized. Adjusted cohort-specific effect estimates were combined by using a random- and fixed-effects meta-analysis.RESULTS:
Women who ate fish >1 time/wk during pregnancy had lower risk of preterm birth than did women who rarely ate fish (≤ 1 time/wk); the adjusted RR of fish intake >1 but <3 times/wk was 0.87 (95% CI 0.82, 0.92), and for intake ≥ 3 times/wk, the adjusted RR was 0.89 (95% CI 0.84, 0.96). Women with a higher intake of fish during pregnancy gave birth to neonates with a higher birth weight by 8.9 g (95% CI 3.3, 14.6 g) for >1 but <3 times/wk and 15.2 g (95% CI 8.9, 21.5 g) for ≥ 3 times/wk independent of gestational age. The association was greater in smokers and in overweight or obese women. Findings were consistent across cohorts.CONCLUSION:
This large, international study indicates that moderate fish intake during pregnancy is associated with lower risk of preterm birth and a small but significant increase in birth weight.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Poluentes Químicos da Água
/
Contaminação de Alimentos
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Alimentos Marinhos
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Fenômenos Fisiológicos da Nutrição Materna
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Nascimento Prematuro
/
Desenvolvimento Fetal
/
Peixes
Tipo de estudo:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Risk_factors_studies
/
Systematic_reviews
Limite:
Animals
/
Female
/
Humans
/
Pregnancy
País/Região como assunto:
Europa
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article