Effect of maternal smoking cessation before and during early pregnancy on fetal and childhood growth.
J Epidemiol
; 24(1): 60-6, 2014.
Article
em En
| MEDLINE
| ID: mdl-24335086
ABSTRACT
BACKGROUND:
Maternal smoking during pregnancy is a major cause of intrauterine growth restriction and childhood obesity, but only a few studies have examined the association of smoking cessation before and during pregnancy with fetal and childhood growth. We examined this association in a prospective cohort study in Japan.METHODS:
Our study included children born between 1991 and 2006 and their mothers. Using a questionnaire, maternal smoking status was recorded at pregnancy. The anthropometric data of the children were collected during a medical check-up at age 3 years. Multiple linear and logistic regression models were used for data analysis stratified by sex.RESULTS:
In total, 2663 mothers reported their smoking status during early pregnancy, and data were collected from 2230 (83.7%) children at age 3 years. Maternal smoking during pregnancy was associated with a significant reduction in birth weight (approximately 120-150 g). Body mass index at age 3 years was significantly higher among boys born to smoking mothers than among boys born to nonsmoking mothers. Maternal smoking during pregnancy was associated with overweight at age 3 years among boys (adjusted odds ratio, 2.4; 95% CI, 1.03-5.4). However, among women who stopped smoking in early pregnancy, there was no increase in the risks of a small for gestational age birth or childhood overweight at age 3 years.CONCLUSIONS:
Children born to mothers who stopped smoking before or during early pregnancy had appropriate fetal and childhood growth.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Efeitos Tardios da Exposição Pré-Natal
/
Fumar
/
Desenvolvimento Infantil
/
Abandono do Hábito de Fumar
/
Desenvolvimento Fetal
Tipo de estudo:
Observational_studies
/
Prognostic_studies
Limite:
Adult
/
Child, preschool
/
Female
/
Humans
/
Male
/
Pregnancy
País/Região como assunto:
Asia
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article