Addition of in-vitro generated endothelial microparticles to von-Willebrand plasma improves primary and secondary hemostasis.

Trummer, Arne; Werwitzke, Sonja; Wermes, Cornelia; Ganser, Arnold; Birschmann, Ingvild; Budde, Ulrich; Tiede, Andreas

Trummer, Arne; Werwitzke, Sonja; Wermes, Cornelia; Ganser, Arnold; Birschmann, Ingvild; Budde, Ulrich; Tiede, Andreas.

Afiliação

Trummer A; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany. Electronic address: trummer.arne@mh-hannover.de.
Werwitzke S; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
Wermes C; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
Ganser A; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
Birschmann I; Institute for Laboratory and Transfusion Medicine, Heart and Diabetes Center, Ruhr University Bochum, Bad Oeynhausen, Germany.
Budde U; Asklepios Clinic Altona, Medilys Central Laboratory Coagulation, Hamburg, Germany.
Tiede A; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.

Thromb Res ; 133(3): 445-50, 2014 Mar.

Article em En | MEDLINE | ID: mdl-24359969

Assuntos

Antibacterianos/farmacologia; Micropartículas Derivadas de Células/metabolismo; Células Endoteliais/metabolismo; Hemostasia/efeitos dos fármacos; Doenças de von Willebrand/sangue; Fator de von Willebrand/metabolismo; Adolescente; Adulto; Plaquetas/citologia; Plaquetas/efeitos dos fármacos; Plaquetas/metabolismo; Linhagem Celular Tumoral; Criança; Pré-Escolar; Feminino; Humanos; Masculino; Agregação Plaquetária/efeitos dos fármacos; Ristocetina/farmacologia; Trombina/biossíntese; Adulto Jovem; Doenças de von Willebrand/terapia

Palavras-chave

Microparticles; Ristocetin-induced platelet aggregation; Thrombin generation; Von-Willebrand disease

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças de von Willebrand / Fator de von Willebrand / Células Endoteliais / Micropartículas Derivadas de Células / Hemostasia / Antibacterianos Limite: Adolescent / Adult / Child / Child, preschool / Female / Humans / Male Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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