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Pazopanib exposure decreases as a result of an ifosfamide-dependent drug-drug interaction: results of a phase I study.
Hamberg, P; Boers-Sonderen, M J; van der Graaf, W T A; de Bruijn, P; Suttle, A B; Eskens, F A L M; Verweij, J; van Herpen, C M L; Sleijfer, S.
Afiliação
  • Hamberg P; Department of Medical Oncology and Cancer Genomics Netherlands, Erasmus MC Cancer Institute, Daniel den Hoed Cancer Center, Rotterdam, The Netherlands.
  • Boers-Sonderen MJ; Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.
  • van der Graaf WT; Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.
  • de Bruijn P; Department of Medical Oncology and Cancer Genomics Netherlands, Erasmus MC Cancer Institute, Daniel den Hoed Cancer Center, Rotterdam, The Netherlands.
  • Suttle AB; GlaxoSmithKline, Clinical Pharmacology Modeling and simulation, Research Triangle Park, NC, USA.
  • Eskens FA; Department of Medical Oncology and Cancer Genomics Netherlands, Erasmus MC Cancer Institute, Daniel den Hoed Cancer Center, Rotterdam, The Netherlands.
  • Verweij J; Department of Medical Oncology and Cancer Genomics Netherlands, Erasmus MC Cancer Institute, Daniel den Hoed Cancer Center, Rotterdam, The Netherlands.
  • van Herpen CM; Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.
  • Sleijfer S; Department of Medical Oncology and Cancer Genomics Netherlands, Erasmus MC Cancer Institute, Daniel den Hoed Cancer Center, Rotterdam, The Netherlands.
Br J Cancer ; 110(4): 888-93, 2014 Feb 18.
Article em En | MEDLINE | ID: mdl-24366297

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirimidinas / Sulfonamidas / Protocolos de Quimioterapia Combinada Antineoplásica / Ifosfamida / Neoplasias Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2014 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirimidinas / Sulfonamidas / Protocolos de Quimioterapia Combinada Antineoplásica / Ifosfamida / Neoplasias Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2014 Tipo de documento: Article