Associated factors with syphilis among human immunodeficiency virus-infected men who have sex with men in Taiwan in the era of combination antiretroviral therapy.
J Microbiol Immunol Infect
; 47(6): 533-41, 2014 Dec.
Article
em En
| MEDLINE
| ID: mdl-24388575
ABSTRACT
BACKGROUND/PURPOSE:
Little is known about the factors associated with syphilis among human immunodeficiency virus (HIV)-infected men who have sex with men (MSM) with access to combination antiretroviral therapy (cART) in Taiwan, where MSM has re-emerged as the leading risk group for HIV transmission.METHODS:
From March to October 2011, MSM who regularly attended HIV clinics at a university hospital were invited to participate in the study. A structured questionnaire interview was conducted to collect information on sociodemographic characteristics, immunologic and virologic status, sexual partners and patterns of sexual behavior, and use of recreational drugs.RESULTS:
During the study period, 310 HIV-infected MSM with a mean age of 35.5 years were enrolled, of which 82.3% (n = 255) were sexually active and 37.4% (n = 116) used recreational drugs in the past 6 months. Syphilis was self-reported in 46.5% (n = 144) of the participants after HIV infection was diagnosed and 37.5% (112/299) had serologic evidence of syphilis within 1 year before enrollment. Multivariate logistic regression analysis limited to those who were receiving cART showed that higher CD4 counts [adjusted odds ratio (AOR) 1.17; 95% confidence interval (CI) 1.02-1.34], lower educational achievement (AOR 1.95; 95% CI 1.05-3.63), serosorting (AOR 3.32; 95% CI 1.04-10.63), and use of recreational drugs (AOR 2.55; 95% CI 1.26-5.13) were associated with syphilis.CONCLUSION:
Improved immune status, lower educational achievement, serosorting, and use of recreational drugs were associated with syphilis among HIV-infected MSM who were receiving cART. These findings suggest that strengthening client-specific counseling is needed to reduce risks for syphilis among HIV-infected MSM in Taiwan.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Sífilis
/
Infecções por HIV
/
Homossexualidade Masculina
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Terapia Antirretroviral de Alta Atividade
/
Coinfecção
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Prevalence_studies
/
Qualitative_research
/
Risk_factors_studies
Limite:
Adult
/
Humans
/
Male
País/Região como assunto:
Asia
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article