A new itch to scratch for TSLP.

Turner, Matthew J; Zhou, Baohua

Turner, Matthew J; Zhou, Baohua.

Afiliação

Turner MJ; Department of Dermatology, Indiana University School of Medicine, Indianapolis, IN 46202, USA; Richard L. Roudebush Veterans Affairs Medical Center, Indianapolis, IN 46202, USA.
Zhou B; Department of Pediatrics and Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN 46202, USA. Electronic address: zhoub@iu.edu.

Trends Immunol ; 35(2): 49-50, 2014 Feb.

Article em En | MEDLINE | ID: mdl-24412411

ABSTRACT

ABSTRACT

Atopic dermatitis (AD) is characterized by allergic inflammation and itch. Thymic stromal lymphopoietin (TSLP) is a pro-allergic cytokine implicated in AD. A paper in Cell transforms the understanding of the functional repertoire of TSLP in general and in AD in particular showing that TSLP can directly stimulate sensory neurons and provoke itch.

Assuntos

Citocinas/metabolismo; Dermatite Atópica/patologia; Transdução de Sinais; Animais; Humanos

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Citocinas / Dermatite Atópica Limite: Animals / Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google