3-Isopropyl-1-{2-[(1-methyl-1H-tetra-zol-5-yl)sulfan-yl]acet-yl}-2,6-di-phenyl-piperidin-4-one hemihydrate.
Acta Crystallogr Sect E Struct Rep Online
; 69(Pt 11): o1598, 2013 Oct 02.
Article
em En
| MEDLINE
| ID: mdl-24454052
ABSTRACT
In the title compound, C24H27N5O2S·0.5H2O, the piperidine ring adopts a distorted boat conformation. The phenyl rings subtend dihedral angles of 69.7â
(1) and 88.7â
(1)° with the best plane through the piperidine moiety. In the crystal, symmetry-related mol-ecules are linked through a network of C-Hâ¯O and C-Hâ¯N inter-actions, the former connecting them into zigzag chains along the c-axis direction and the latter forming an R (2) 2(4)motif. The dimer formation (C-Hâ¯N) and the repetition of symmetry-related molecules (C-Hâ¯O) along the b-axis direction stabilize the packing mode. The water mol-ecule is located on a twofold rotation axis.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article