[The importance of lung volumes in the investigation of heavy smokers]. / Place de la distension pulmonaire dans l'exploration des gros fumeurs de cigarettes.
Rev Mal Respir
; 31(1): 29-40, 2014 Jan.
Article
em Fr
| MEDLINE
| ID: mdl-24461440
ABSTRACT
INTRODUCTION:
Lung hyperinflation (LH) has become a major concern in the management of chronic obstructive pulmonary disease (COPD). MAINAIM:
To evaluate the role of lung volumes in the positive diagnosis of COPD and in the assessment of airway obstruction reversibility. POPULATION ANDMETHODS:
Three hundred and sixty-six male smokers over the age of 35 with more than 40 pack-years exposure were included in the study. Plethysmographic data were determined before/after taking a bronchodilator (BBD, ABD). Applied definitions airflow obstruction BBD FEV1/FVC<0.70. LH BBD residual volume (RV)>upper limit of normal. Expressions of reversibility Δvariable=(ABD-BBD) values; Δinit%=Δvariable/BBD value and Δref%=Δvariable/reference value. A 12%init and a 0.2L increase in either FEV1 or FVC or a 10%ref or - 300 mL decrease in RV were considered as clinically significant.RESULTS:
Over the 85 smokers without airflow obstruction, 68% had LH. In the hyperinflated group (n=314), and compared to changes in FEV1 and FVC, these RV changes detected more respondents (54% for FEV1 and FVC vs. 65% for RV, P=0.002). This was not the case for the group free from LH (n=52) (23% for FEV1 and FVC vs. 35% for RV, P=0.09). In the 58 hyperinflated groups free from airflow obstruction, and compared to changes in FEV1 and FVC, changes in RV detected more respondents (24% for FEV1 and FVC vs. 71% for RV, P=0.0001).CONCLUSION:
In heavy smokers, it seems essential to include LH as a criterion for a positive diagnosis of COPD and of reversibility evaluation.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Tabagismo
/
Fumar
/
Doença Pulmonar Obstrutiva Crônica
/
Pulmão
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
Limite:
Adult
/
Aged
/
Humans
/
Male
/
Middle aged
Idioma:
Fr
Ano de publicação:
2014
Tipo de documento:
Article