Duchenne muscular dystrophy gene expression in normal and diseased human muscle.
Science
; 239(4846): 1418-20, 1988 Mar 18.
Article
em En
| MEDLINE
| ID: mdl-2450401
ABSTRACT
A probe for the 5' end of the Duchenne muscular dystrophy (DMD) gene was used to study expression of the gene in normal human muscle, myogenic cell cultures, and muscle from patients with DMD. Expression was found in RNA from normal fetal muscle, adult cardiac and skeletal muscle, and cultured muscle after myoblast fusion. In DMD muscle, expression of this portion of the gene was also revealed by in situ RNA hybridization, particularly in regenerating muscle fibers.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Regulação da Expressão Gênica
/
Músculos
/
Distrofias Musculares
Limite:
Humans
Idioma:
En
Ano de publicação:
1988
Tipo de documento:
Article