Synthesis, nitric oxide release, and &#945;-glucosidase inhibition of nitric oxide donating apigenin and chrysin derivatives.

Wang, Qi-Qin; Cheng, Ning; Yi, Wen-Bing; Peng, Sheng-Ming; Zou, Xiao-Qing

Synthesis, nitric oxide release, and α-glucosidase inhibition of nitric oxide donating apigenin and chrysin derivatives.

Wang, Qi-Qin; Cheng, Ning; Yi, Wen-Bing; Peng, Sheng-Ming; Zou, Xiao-Qing.

Afiliação

Wang QQ; Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Xiangtan 411105, China; Department of Pharmacy and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine & New Dr
Cheng N; Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Xiangtan 411105, China.
Yi WB; Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Xiangtan 411105, China.
Peng SM; Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Xiangtan 411105, China; Postdoctoral Programme of Chemical Engineering & Technology, Xiangtan University, Xiangtan 411105, China. Electronic address: pengshe
Zou XQ; Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Xiangtan 411105, China.

Bioorg Med Chem ; 22(5): 1515-21, 2014 Mar 01.

Article em En | MEDLINE | ID: mdl-24508143

Assuntos

Apigenina/síntese química; Complicações do Diabetes/prevenção & controle; Diabetes Mellitus/tratamento farmacológico; Flavonoides/síntese química; Hipoglicemiantes/farmacologia; Óxido Nítrico/síntese química; alfa-Glucosidases/síntese química; Apigenina/química; Flavonoides/química; Humanos; Estrutura Molecular; Óxido Nítrico/química; Relação Estrutura-Atividade; alfa-Glucosidases/química

Palavras-chave

Apigenin derivatives; Chrysin derivatives; NO donor; NO-releasing; α-Glucosidase inhibitor

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Flavonoides / Complicações do Diabetes / Apigenina / Diabetes Mellitus / Alfa-Glucosidases / Hipoglicemiantes / Óxido Nítrico Limite: Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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