Enhancement of natural killer activity in human peripheral blood by flavone acetic acid.
J Natl Cancer Inst
; 80(7): 521-5, 1988 Jun 01.
Article
em En
| MEDLINE
| ID: mdl-2452890
ABSTRACT
Natural killer cell activity and interferon (IFN) production were measured in 6 patients receiving flavone acetic acid for treatment of cancer. Natural killer cell activity was significantly increased in 3 of 6 patients receiving 6.4 g of flavone acetic acid/m2 by 3-hour iv infusion. Analysis of cell surface markers failed to reveal significant changes in any cell population. There was no evidence of induction of IFN-gamma, but 3 of 4 patients tested had evidence of induction of type I IFN, as measured in a virus neutralization assay.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Flavonoides
/
Células Matadoras Naturais
/
Antineoplásicos
Limite:
Adult
/
Aged
/
Female
/
Humans
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Male
/
Middle aged
Idioma:
En
Ano de publicação:
1988
Tipo de documento:
Article