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Mitochondrial DNA variant in COX1 subunit significantly alters energy metabolism of geographically divergent wild isolates in Caenorhabditis elegans.
Dingley, Stephen D; Polyak, Erzsebet; Ostrovsky, Julian; Srinivasan, Satish; Lee, Icksoo; Rosenfeld, Amy B; Tsukikawa, Mai; Xiao, Rui; Selak, Mary A; Coon, Joshua J; Hebert, Alexander S; Grimsrud, Paul A; Kwon, Young Joon; Pagliarini, David J; Gai, Xiaowu; Schurr, Theodore G; Hüttemann, Maik; Nakamaru-Ogiso, Eiko; Falk, Marni J.
Afiliação
  • Dingley SD; Division of Human Genetics, Department of Pediatrics, The Children's Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.
  • Polyak E; Division of Human Genetics, Department of Pediatrics, The Children's Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.
  • Ostrovsky J; Division of Human Genetics, Department of Pediatrics, The Children's Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.
  • Srinivasan S; Department of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
  • Lee I; Dankook University College of Medicine, Yongin-si, Gyeonggi-do, South Korea.
  • Rosenfeld AB; Department of Molecular Pharmacology and Therapeutics, Loyola University Health Sciences Division, Maywood, IL, 60153, USA.
  • Tsukikawa M; Division of Human Genetics, Department of Pediatrics, The Children's Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.
  • Xiao R; Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, 19104, USA.
  • Selak MA; Mitochondria Research Core Facility, The Children's Hospital of Philadelphia Research Institute, Philadelphia, PA, 19104, USA.
  • Coon JJ; Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI, 53706, USA; Department of Chemistry, University of Wisconsin-Madison, Madison, WI, 53706, USA; Genome Center of Wisconsin, University of Wisconsin-Madison, Madison, WI, 53706, USA.
  • Hebert AS; Department of Chemistry, University of Wisconsin-Madison, Madison, WI, 53706, USA; Genome Center of Wisconsin, University of Wisconsin-Madison, Madison, WI, 53706, USA.
  • Grimsrud PA; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI, 53706, USA.
  • Kwon YJ; Division of Human Genetics, Department of Pediatrics, The Children's Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA. Electronic address: kwonyo@sas.upenn.edu.
  • Pagliarini DJ; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI, 53706, USA.
  • Gai X; Department of Molecular Pharmacology and Therapeutics, Loyola University Health Sciences Division, Maywood, IL, 60153, USA.
  • Schurr TG; Department of Anthropology, University of Pennsylvania, Philadelphia, PA, 19104, USA.
  • Hüttemann M; Center for Molecular Medicine and Genetics and Cardiovascular Research Institute, Wayne State University School of Medicine, Detroit, MI, 48201, USA.
  • Nakamaru-Ogiso E; Department of Biochemistry and Biophysics, University of Pennsylvania School of Medicine, Philadelphia, PA, 19104, USA.
  • Falk MJ; Division of Human Genetics, Department of Pediatrics, The Children's Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA. Electronic address: falkm@email.chop.edu.
J Mol Biol ; 426(11): 2199-216, 2014 May 29.
Article em En | MEDLINE | ID: mdl-24534730
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: DNA Mitocondrial / Caenorhabditis elegans / Complexo IV da Cadeia de Transporte de Elétrons / Proteínas de Caenorhabditis elegans / Metabolismo Energético / Mitocôndrias Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2014 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: DNA Mitocondrial / Caenorhabditis elegans / Complexo IV da Cadeia de Transporte de Elétrons / Proteínas de Caenorhabditis elegans / Metabolismo Energético / Mitocôndrias Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2014 Tipo de documento: Article