Platinum-catalyzed anti-stereocontrolled ring-opening of oxabicyclic alkenes with Grignard reagents.
Org Biomol Chem
; 12(13): 2080-6, 2014 Apr 07.
Article
em En
| MEDLINE
| ID: mdl-24549179
ABSTRACT
A new platinum-catalyzed anti-stereocontrolled ring-opening of oxabicyclic alkenes with various Grignard reagents was reported, which afforded the corresponding anti-2-substituted-1,2-dihydronaphthalen-1-ol products with moderate to good yields in the presence of a catalytic amount of Pt(PPh3)4 (2.5 mol%) under mild conditions. The effects of catalyst loading, solvent and temperature on the yield were also investigated. Furthermore, the trans-configuration of the product 5i was confirmed by X-ray diffraction analysis.
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1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Compostos Organometálicos
/
Platina
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Compostos Bicíclicos com Pontes
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Alcenos
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article